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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
21.52
Human Site:
S278
Identified Species:
36.41
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S278
G
K
D
V
R
L
V
S
L
G
S
R
Q
N
L
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S278
G
K
D
V
R
L
V
S
L
G
S
R
Q
N
L
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S259
G
K
D
V
R
L
V
S
L
G
S
R
Q
N
L
Dog
Lupus familis
XP_543872
907
102087
S259
G
K
D
T
R
L
V
S
L
G
S
R
Q
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
M260
M
N
D
R
C
V
D
M
Q
R
S
K
R
E
K
Rat
Rattus norvegicus
XP_001070646
845
94905
N249
Q
A
S
C
P
F
Y
N
H
E
Q
M
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
S276
G
K
E
T
R
L
A
S
L
G
S
R
Q
S
L
Chicken
Gallus gallus
XP_416375
940
105739
S292
G
K
D
T
R
L
V
S
L
G
S
R
Q
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
M267
M
N
E
R
C
L
E
M
Q
K
N
K
H
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
C246
V
G
L
M
N
E
R
C
L
D
M
A
T
K
K
Honey Bee
Apis mellifera
XP_001121183
769
88327
F209
T
T
T
T
N
C
P
F
I
P
G
N
Q
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
E220
Q
L
G
K
V
G
K
E
L
K
A
C
P
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
P272
D
E
K
V
K
Y
L
P
L
A
S
K
K
Q
L
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
N366
P
A
S
V
P
T
P
N
P
Q
E
K
P
A
K
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
100
100
93.3
N.A.
13.3
6.6
N.A.
73.3
93.3
N.A.
6.6
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
20
N.A.
86.6
93.3
N.A.
26.6
N.A.
13.3
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
8
0
0
8
8
8
0
8
0
% A
% Cys:
0
0
0
8
15
8
0
8
0
0
0
8
0
0
0
% C
% Asp:
8
0
43
0
0
0
8
0
0
8
0
0
0
8
0
% D
% Glu:
0
8
15
0
0
8
8
8
0
8
8
0
8
15
0
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
43
8
8
0
0
8
0
0
0
43
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
43
8
8
8
0
8
0
0
15
0
29
8
8
29
% K
% Leu:
0
8
8
0
0
50
8
0
65
0
0
0
0
8
65
% L
% Met:
15
0
0
8
0
0
0
15
0
0
8
8
0
0
0
% M
% Asn:
0
15
0
0
15
0
0
15
0
0
8
8
0
36
0
% N
% Pro:
8
0
0
0
15
0
15
8
8
8
0
0
15
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
15
8
8
0
50
8
0
% Q
% Arg:
0
0
0
15
43
0
8
0
0
8
0
43
8
0
0
% R
% Ser:
0
0
15
0
0
0
0
43
0
0
58
0
0
8
0
% S
% Thr:
8
8
8
29
0
8
0
0
0
0
0
0
8
0
0
% T
% Val:
8
0
0
36
8
8
36
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _